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KMID : 0043319980210060744
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Archives of Pharmacal Research
1998 Volume.21 No. 6 p.744 ~ p.748
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Synthesis of Praziquantel Derivatives and Their In Vitro Activity Against Adult Clonorchis sinensis
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Kim Choong-Sup
Min Duk-Young
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Abstract
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Several praziquantel derivatives have been prepared by the acylation of compound 5, and examined on their biological activity in vitro agninst adult clonorchis sinensis collected from rabbits infected with metacercariae which was isolated from Pseudorasbora parva, a second intermediate host, captured in Nakdong river in Korea.
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KEYWORD
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Praziquantel derivatives, Anthelmintic activity, Clonorchis sinensis
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